Searchable abstracts of presentations at key conferences in endocrinology

ea0056gp255 | Thyroid non cancer - Autoimmune Thyroid disease/pregnancy | ECE2018

MicroRNA-4443 causes CD4+T cells dysfunction by targeting TRAF4 in Graves’ disease

Qi Yicheng , Ning Guang , Wang Shu

Context: Aberrant CD4+T cell function plays a critical role in the process of GravesÂ’ disease (GD). MicroRNAs (miRNAs) are important regulators of T cell activation, proliferation and cytokine production. However, the contribution of miRNAs to CD4+T cell dysfunction in GD remains unclear.Objective: To investigate how certain miRNA causes aberrant CD4+T cell function in GD patients.Methods: We compared the expression pattern of...